Education
- Postdoctoral, University of Toronto
- Ph.D., University of Waterloo
Courses Taught at ACPHS
- Pharmacokinetics
- Pharmaceutical Analysis
- Pharmaceutics
Research Interests
- Development of miniaturized analytical technology for pharmacokinetic studies and therapeutic drug monitoring, with the purpose of creating personalized therapeutic devices that integrate chemical analysis, decision, and drug delivery.
- Pharmacokinetic-pharmacodynamic modeling of anticancer drugs
- Minimally invasive sampling and analysis of drugs and endogenous compounds in biological samples
Selected Publications
Mall I, Musteata FM. Transdermal Sampling of Vitamin D3 and 25-Hydroxyvitamin D3. Bioanalysis, 11(2), Epub ahead of print , DOI 10.4155/bio-2018-0138, 2018 (corresponding author).
Dajana Vuckovic, Erasmus Cudjoe, Florin Marcel Musteata & Janusz Pawliszyn: “Automated solid-phase microextraction and thin-film microextraction for high-throughput analysis of biological fluids and ligand–receptor binding studies”, Nature Protocols, 5(1), 140-161, 2010
Musteata, Marcel Florin: “Pharmacokinetic Applications of Microdevices and Microsampling Techniques”, Bioanalysis, 1(1), 171-185, 2009
Yanwei Zhan, Tibebe Lemma, Marcel Florin Musteata, and Janusz Pawliszyn: “Development of a Simple Ampholyte-Free Isoelectric Focusing Slab Electrophoresis for Protein Fractionation”, Journal of Chromatography A, in press, 2009
Musteata Florin Marcel, de Lannoy I, Gien B, and Pawliszyn Janusz: “Blood sampling without blood draws for in vivo pharmacokinetic studies in rats”, Journal of Pharmaceutical and Biomedical Analysis, 47, 907-912, 2008
Musteata, Florin Marcel and Janusz Pawliszyn: “In Vivo Sampling with Solid Phase Microextraction” Journal of Biochemical and Biophysical Methods, 70(2), 181-193, 2007
Xu Zhang, Ali Es-haghi, Florin Marcel Musteata, Gangfeng Ouyang, and Janusz Pawliszyn: “Quantitative In Vivo Micro-sampling for Pharmacokinetic Studies Based on an Integrated Solid-Phase Microextraction System”, Analytical Chemistry, 79(12), 4507-4513, 2007
Musteata, Florin Marcel and Janusz Pawliszyn: “Determination of Free Concentration of Paclitaxel in Liposome Formulations” Journal of Pharmacy & Pharmaceutical Sciences, 9 (2): 231-237, 2006
Musteata, Florin Marcel, Musteata, M., Pawliszyn, J. “Fast in vivo microextraction: a new tool for clinical analysis”, Clinical Chemistry, 52(4), 708-715, 2006
Musteata, Florin Marcel, J. Pawliszyn, Qian M., Wu J.T., Miwa G.T. “Determination of Drug Plasma Protein Binding by Solid Phase Microextraction”. Journal of Pharmaceutical Sciences, 95(8):1712-1722, 2006
Conferences and Presentations
Mall I, Zheng H, Musteata FM. Transdermal Sampling of Vitamin D3 and 25-Hydroxyvitamin D3. AAPS-NERDG, Farmington CT, April 2018.
Extramural Grants
Role: Co-Principal Investigator: Marcel Musteata (Co-PI: Michael Kane, ACPHS)
Project Title: Simultaneous Determination of Free, Total, and Normalized Concentrations of Bioactive Compounds
Grantor: National Institutes of Health, National Institute of General Medical Sciences
Grant Number: 1R15GM126510-01
Amount: $480,000
Term: 2018-2021
Honors, Awards and Appointments
Associate Editor for Bioanalysis