Education
- M.Sc., Clinical Investigation, Northwestern University, Chicago, IL
- Infectious Diseases Pharmacotherapy Fellow, Department of Pharmacy Practice, Midwestern University, Downers Grove, IL
- PGY-1 Pharmacy Practice Resident, Beth Israel Deaconess Medical Center, Boston, MA
- Pharm.D., Northeastern University, Boston, MA
Research Interests
- Antimicrobial pharmacokinetics and pharmacodynamics in sepsis
- Ventilator-associated pneumonia
- Multi-drug resistant Gram-negative bacteria
Selected Publications
Rhodes NJ, Prozialeck WC, Lodise TP, Venkatesan N, O'Donnell JN, Pais G, Cluff C, Lamar PC, Neely MN, Gulati A, Scheetz MH. Evaluation of vancomycin exposures associated with elevations in novel urinary biomarkers of acute kidney injury in vancomycin-treated rats. Antimicrobial Agents and Chemotherapy. 2016. doi: 10.1128/aac.00591-16.
O’Donnell JN, O’Donnell EP, Gulati A, Lavhale MS, Kumar EJ, Scheetz MH. Centhaquin citrate pharmacokinetics in a dog model. J Pharm Pharmacol 2016; Accepted, pending publication.
O’Donnell JN, Miglis CM, Lee JY, Tuvell M, Lertharakul T, Scheetz MH. Carbapenem susceptibility breakpoints, clinical implications with the moving target. Expert Rev Anti Infect Ther 2016; 14: 389-401.
O’Donnell JN, Venkatesan N, Manek M, Rhodes NJ, Scheetz MH. Visual and absorbance analyses of vancomycin and piperacillin-tazobactam incompatibilities at a range of commonly utilized doses. Am J Health Syst Pharm 2016; 4: 241-246.
Rhodes NJ, O’Donnell JN, Lizza BD, Mclaughlin MM, Esterly JS, Scheetz MH. Tree based models for the prediction of mortality in Gram negative bacteremia: avoid putting the CART before the horse. Antimicrob Agents Chemother 2016; 60: 838-844.
O’Donnell JN, Gulati A, Lavhale MS, Sharma SS, Patel AJ, Rhodes NJ, Scheetz MH. Pharmacokinetics of centhaquin citrate in a rat model. J Pharm Pharmacol 2016; 68: 56-62.
Biehle LR, Cottreau JM, Thompson DJ, Filipek RL, O’Donnell JN, Lasco TM, Mahoney MV, Hirsch EB. Outcomes and risk factors for mortality among patients treated with carbapenems for Klebsiella spp. bacteremia. PLoS One. 2015 Nov 30;10(11):e0143845.
Conferences and Presentations
Bidell MR, Novak G, Singh G, Bratek B, Duru O, Mitchell C, O’Donnell JN. A multicenter Evaluation of Outcomes Associated With Oral Vancomycin Dose in Patients With Clostridium difficile Infection. IDWeek 2018, San Francisco CA, October 2018.
Lodise TP, Smith NM, Holden P, O’Donnell JN, Bedard T, Bonomo RA, Tsuji BT. Efficacy of Ceftazidime–Avibactam in Combination with Aztreonam (COMBINE): Solutions for Metallo-β-Lactamase Producing-Enterobacteriaceae (MBL). IDWeek 2018, San Francisco CA, October 2018.
Avedissian S, Liu J, O’Donnell JN, Pais G, Becher L, Joshi M, Prozialeck W, Lamar P, Lodise TP, Scheetz MH. 24-Hour Pharmacokinetic Relationships for Intravenous Vancomycin and Novel Urinary Biomarkers of Acute Kidney Injury. IDWeek 2018, San Francisco CA, October 2018.
Publications
Bidell MR, Patel N, O'Donnell JN. Optimal treatment of MSSA bacteraemias: a meta-analysis of cefazolin versus antistaphylococcal penicillins. Journal of Antimicrobial Chemotherapy 2018 Oct 1;73(10):2643-2651. doi: 10.1093/jac/dky259.
Wang SK, Gilchrist A, Loukitcheva A, Plotkin BJ, Sigar IM, Gross AE, O'Donnell JN, Pettit N, Buros A, O'Driscoll T, Rhodes NJ, Bethel C, Segreti J, Charnot-Katsikas A, Singh K, Scheetz MH. Prevalence of a Cefazolin Inoculum Effect Associated with blaZ Gene Types among Methicillin-Susceptible Staphylococcus aureus Isolates from Four Major Medical Centers in Chicago. Antimicrobial Agents and Chemotherapy 2018 Jul 27;62(8). pii: e00382-18. doi: 10.1128/AAC.00382-18.
O'Donnell JN, Rhodes NJ, Lopez J, Jett R, Scheetz MH. Carbapenems vs. alternative β-lactams for the treatment of nosocomial pneumonia: A systematic review and meta-analysis. International Journal of Antimicrobial Agents 2018 Oct;52(4):451-458. doi: 10.1016/j.ijantimicag.2018.04.011.
Rhodes NJ, Cruce CE, O'Donnell JN, Wunderink RG, Hauser AR. Resistance Trends and Treatment Options in Gram-Negative Ventilator-Associated Pneumonia. Current Infectious Disease Reports 2018 Mar 6;20(2):3. doi: 10.1007/s11908-018-0609.
Crew PE, Rhodes NJ, O'Donnell JN, Miglis C, Gilbert EM, Zembower TR, Qi C, Silkaitis C, Sutton SH, Scheetz MH. Correlation between hospital-level antibiotic consumption and incident health care facility-onset Clostridium difficile infection. American Journal of Infection Control 2018 Mar;46(3):270-275. doi: 10.1016/j.ajic.2017.09.015.
Rhodes NJ, Liu J, O'Donnell JN, Dulhunty JM, Abdul-Aziz MH, Berko PY, Nadler B, Lipman J, Roberts JA. Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine 2018 Feb;46(2):236-243. doi: 10.1097/CCM.0000000000002836.