Associate Professor
Focus: Genetics/Molecular Virology
518-694-7116
Binshan.Shi@acphs.edu
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Education
- Ph.D., Zhejiang University, P. R. China
- M.Sc., Zhejiang University, P. R. China
- B.Sc., Zhejiang University, P. R. China
Courses Taught at ACPHS
- BIO 225 Genetics
- BHS 740 Genetics and Molecular Basis of Disease
- BHS 345/745 Molecular Diagnosis
- BHS 750 Flow Cytometry
- BIO 345/660 Journal Club
- BHS 490 Independent Research
Research Interests
Dr. Shi is a molecular biologist and molecular virologist. He has worked on the research and molecular diagnosis of HIV-1 in recent years. Dr. Shi’s research interests are mainly focused on two areas:
Research to understand the molecular basis of disease pathogenesis by using advanced molecular biology, virology, molecular genetics, and bioinformatics approaches. Methods used in lab include a) HIV-1 infectious molecular clone, recombinant virus, and reporter gene technologies to study HIV phenotype such as infection and replication; b) HIV-1 single genome amplification, sequencing and bioinformatics tools to understand the genotype changes and its association with disease progression.
Design and develop nucleic acid based molecular diagnosis assays for the detecting of infectious diseases, and its application for the monitoring of disease progression and the management of treatment. DNA amplification technology, fluorescence based quantification method, and novel mutation detection approaches were used in lab.
Patents
- Dr. Shi is the inventor of the International Patent “Detection of X4 Strains of HIV-1 by Heteroduplex Tracking Assay” (WO2011032078).
Professional Affiliations
- Member of the International AIDS Research Society.
- Member of the American Society for Microbiology
- Reviewer for Journal of Clinical Microbiology.
- American Society for Clinical Laboratory Sciences.
Professional Certifications
- New York State Clinical Laboratory License Technologist.
- Clinical Molecular Biologist (American Society of Clinical Pathologists).
Previous Positions or Appointments
- Research Scientist, Wadsworth Center, New York State Department of Health
- Assistant Professor, Zhejiang University
Selected Publications/Conference Presentations